Cannabis and Seizure Disorder

How can plant-based cannabinoids offer benefits for Seizure Disorder? Read Bonni Goldstein MD's summary of the research on cannabis and Seizure Disorder.

One of the most studied conditions for cannabinoid treatment is seizure disorders, including epilepsy. Cannabidiol (CBD) has been extensively studied and is now considered an acceptable and effective treatment for intractable epilepsy, with a favorable safety profile. Multiple randomized controlled trials have shown that CBD can significantly reduce seizure frequency, severity and duration. Beyond seizure control, studies suggest that CBD may also improve alertness, behavior, and quality of life for those struggling with seizures. Other cannabinoids, such as cannabidivarin (CBDV), show promise as anticonvulsants and may improve benefits in combination regimens.

Sources

Ong, Marjorie Jia Yi, et al. "The use of cannabidiol as adjunctive therapy in adult patients with drug-resistant epilepsy: a systematic review and meta-analysis." Therapeutic Advances in Neurological Disorders 18 (2025): 17562864251313914.; da Silva Rodrigues, Douglas, Adria Santos Bastos Soares, and Claudia Dizioli Franco Bueno. "The use of cannabinoids in children with epilepsy: A systematic review." Epilepsy & Behavior 145 (2023): 109330.

With over two decades of clinical experience, Dr. Goldstein is the CEO and co-founder of Goldstein Wellness and serves as the Medical Director/Owner of Canna-Centers Wellness & Education. Her patient roster, numbering over 20,000 individuals, includes more than two thousand children who have benefited from medical cannabis under her care.
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