Cannabis and Spasticity

How can plant-based cannabinoids offer benefits for Spasticity? Read Bonni Goldstein MD's summary of the research on cannabis and Spasticity.

Cannabinoids have shown promise in the management of spasticity, a condition characterized by involuntary muscle stiffness and spasms often seen in multiple sclerosis, spinal cord injury, and other neurologic disorders. Through modulation of the endocannabinoid system which promotes homeostasis, cannabinoid compounds can reduce excessive neuronal excitability and improve muscle relaxation. Some clinical studies have demonstrated reductions in spasticity scores, improved mobility, and enhanced quality of life for patients, while maintaining a generally favorable safety profile. CBD, may provide added benefit by reducing inflammation and neuroexcitability associated with spasticity.

Sources

AlHabil, Yazan, et al. "Assessing the Role of Cannabis in Managing Spasticity in Multiple Sclerosis: A Systematic Review and Meta-Analysis." Clinical Therapeutics (2025.; Nielsen, Suzanne, et al. "Cannabinoids for the treatment of spasticity." Developmental Medicine & Child Neurology 61.62019: 631-638.)

With over two decades of clinical experience, Dr. Goldstein is the CEO and co-founder of Goldstein Wellness and serves as the Medical Director/Owner of Canna-Centers Wellness & Education. Her patient roster, numbering over 20,000 individuals, includes more than two thousand children who have benefited from medical cannabis under her care.
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